Durvalumab vs Polatuzumab Vedotin

Durvalumab vs Polatuzumab Vedotin: Overview

This comparison examines the pharmacological differences between Durvalumab and Polatuzumab Vedotin.

Mechanism of Action

Durvalumab: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.

Pharmacokinetics

Half-life: Durvalumab — 17 days.

Chemical Properties

Type: Durvalumab — Antibody; Polatuzumab Vedotin — Antibody drug conjugate.