Durvalumab vs Prednisone

Durvalumab vs Prednisone: Overview

This comparison examines the pharmacological differences between Durvalumab and Prednisone.

Mechanism of Action

Durvalumab: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.

Prednisone: Synthetic corticosteroid; suppresses inflammation via glucocorticoid receptor.

Pharmacokinetics

Half-life: Durvalumab — 17 days; Prednisone — 2-3 hours.

Chemical Properties

Molecular Formula: Prednisone — C21H26O5.

Molecular Weight: Prednisone — 358.4280 g/mol.

Type: Durvalumab — Antibody; Prednisone — Small molecule.