Durvalumab vs Trimethoprim

Durvalumab vs Trimethoprim: Overview

This comparison examines the pharmacological differences between Durvalumab and Trimethoprim.

Mechanism of Action

Durvalumab: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.

Trimethoprim: Dihydrofolate reductase inhibitor (bacterial selective).

Pharmacokinetics

Half-life: Durvalumab — 17 days; Trimethoprim — 8-10 hours.

Chemical Properties

Molecular Formula: Trimethoprim — C14H18N4O3.

Molecular Weight: Trimethoprim — 290.3180 g/mol.

Type: Durvalumab — Antibody; Trimethoprim — Small molecule.