Empagliflozin vs Hydrochlorothiazide

## Empagliflozin vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Empagliflozin** and **Hydrochlorothiazide**.

## Mechanism of Action

**Empagliflozin**: Selective SGLT2 inhibitor reducing renal glucose reabsorption.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Empagliflozin — 12.4 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Empagliflozin — C23H27ClO7; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Empagliflozin — 450.9100 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Empagliflozin — Small molecule; Hydrochlorothiazide — Small molecule.