Enalapril vs Furosemide

Enalapril vs Furosemide: Overview

This comparison examines the pharmacological differences between Enalapril and Furosemide.

Mechanism of Action

Enalapril: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Furosemide: Loop diuretic inhibiting Na-K-2Cl cotransporter.

Pharmacokinetics

Half-life: Enalapril — 11 hours; Furosemide — 2 hours.

Chemical Properties

Molecular Formula: Enalapril — C20H28N2O5; Furosemide — C12H11ClN2O5S.

Molecular Weight: Enalapril — 376.4470 g/mol; Furosemide — 330.7440 g/mol.

Type: Enalapril — Small molecule; Furosemide — Small molecule.