Enalapril vs Lisinopril
Enalapril vs Lisinopril: Overview
This comparison examines the pharmacological differences between Enalapril and Lisinopril.
Mechanism of Action
Enalapril: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.
Lisinopril: ACE inhibitor preventing conversion of angiotensin I to angiotensin II.
Pharmacokinetics
Half-life: Enalapril — 11 hours; Lisinopril — 12 hours.
Chemical Properties
Molecular Formula: Enalapril — C20H28N2O5; Lisinopril — C21H31N3O5.
Molecular Weight: Enalapril — 376.4470 g/mol; Lisinopril — 405.4900 g/mol.
Type: Enalapril — Small molecule; Lisinopril — Small molecule.