Enalapril vs Sildenafil

## Enalapril vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Enalapril** and **Sildenafil**.

## Mechanism of Action

**Enalapril**: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Enalapril — 11 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Enalapril — C20H28N2O5; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Enalapril — 376.4470 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Enalapril — Small molecule; Sildenafil — Small molecule.