Enalapril vs Sildenafil

Enalapril vs Sildenafil: Overview

This comparison examines the pharmacological differences between Enalapril and Sildenafil.

Mechanism of Action

Enalapril: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Sildenafil: Selective PDE5 inhibitor increasing cGMP.

Pharmacokinetics

Half-life: Enalapril — 11 hours; Sildenafil — 4 hours.

Chemical Properties

Molecular Formula: Enalapril — C20H28N2O5; Sildenafil — C22H30N6O4S.

Molecular Weight: Enalapril — 376.4470 g/mol; Sildenafil — 474.5800 g/mol.

Type: Enalapril — Small molecule; Sildenafil — Small molecule.