Enalapril vs Valsartan

Enalapril vs Valsartan: Overview

This comparison examines the pharmacological differences between Enalapril and Valsartan.

Mechanism of Action

Enalapril: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Valsartan: Angiotensin II type 1 receptor blocker.

Pharmacokinetics

Half-life: Enalapril — 11 hours; Valsartan — 6 hours.

Chemical Properties

Molecular Formula: Enalapril — C20H28N2O5; Valsartan — C24H29N5O3.

Molecular Weight: Enalapril — 376.4470 g/mol; Valsartan — 435.5190 g/mol.

Type: Enalapril — Small molecule; Valsartan — Small molecule.