Escitalopram vs Paroxetine

Escitalopram vs Paroxetine: Overview

This comparison examines the pharmacological differences between Escitalopram and Paroxetine.

Mechanism of Action

Escitalopram: S-enantiomer of citalopram; selective serotonin reuptake inhibitor.

Paroxetine: Potent selective serotonin reuptake inhibitor with additional muscarinic and NE reuptake inhibition.

Pharmacokinetics

Half-life: Escitalopram — 27-32 hours; Paroxetine — 21 hours.

Chemical Properties

Molecular Formula: Escitalopram — C20H21FN2O; Paroxetine — C19H20FNO3.

Molecular Weight: Escitalopram — 324.3920 g/mol; Paroxetine — 329.3730 g/mol.

Type: Escitalopram — Small molecule; Paroxetine — Small molecule.