Escitalopram vs Sertraline

Escitalopram vs Sertraline: Overview

This comparison examines the pharmacological differences between Escitalopram and Sertraline.

Mechanism of Action

Escitalopram: S-enantiomer of citalopram; selective serotonin reuptake inhibitor.

Sertraline: Selective serotonin reuptake inhibitor (SSRI).

Pharmacokinetics

Half-life: Escitalopram — 27-32 hours; Sertraline — 26 hours.

Chemical Properties

Molecular Formula: Escitalopram — C20H21FN2O; Sertraline — C17H17Cl2N.

Molecular Weight: Escitalopram — 324.3920 g/mol; Sertraline — 306.2290 g/mol.

Type: Escitalopram — Small molecule; Sertraline — Small molecule.