Fentanyl vs Hydrochlorothiazide

Fentanyl vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between Fentanyl and Hydrochlorothiazide.

Mechanism of Action

Fentanyl: Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

Hydrochlorothiazide: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

Pharmacokinetics

Half-life: Fentanyl — 2-4 hours; Hydrochlorothiazide — 6-15 hours.

Chemical Properties

Molecular Formula: Fentanyl — C22H28N2O; Hydrochlorothiazide — C7H8ClN3O4S2.

Molecular Weight: Fentanyl — 336.4700 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

Type: Fentanyl — Small molecule; Hydrochlorothiazide — Small molecule.