Fentanyl vs Oxycodone
Fentanyl vs Oxycodone: Overview
This comparison examines the pharmacological differences between Fentanyl and Oxycodone.
Mechanism of Action
Fentanyl: Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.
Oxycodone: Semisynthetic mu-opioid receptor agonist.
Pharmacokinetics
Half-life: Fentanyl — 2-4 hours; Oxycodone — 3-5 hours.
Chemical Properties
Molecular Formula: Fentanyl — C22H28N2O; Oxycodone — C18H21NO4.
Molecular Weight: Fentanyl — 336.4700 g/mol; Oxycodone — 315.3640 g/mol.
Type: Fentanyl — Small molecule; Oxycodone — Small molecule.