Fentanyl vs Upadacitinib

Fentanyl vs Upadacitinib: Overview

This comparison examines the pharmacological differences between Fentanyl and Upadacitinib.

Mechanism of Action

Fentanyl: Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

Upadacitinib: Selective JAK1 inhibitor reducing signaling from cytokines implicated in autoimmune diseases.

Pharmacokinetics

Half-life: Fentanyl — 2-4 hours; Upadacitinib — 9-14 hours.

Chemical Properties

Molecular Formula: Fentanyl — C22H28N2O; Upadacitinib — C17H19F3N6O.

Molecular Weight: Fentanyl — 336.4700 g/mol; Upadacitinib — 380.3700 g/mol.

Type: Fentanyl — Small molecule; Upadacitinib — Small molecule.