Furosemide vs Losartan

Furosemide vs Losartan: Overview

This comparison examines the pharmacological differences between Furosemide and Losartan.

Mechanism of Action

Furosemide: Loop diuretic inhibiting Na-K-2Cl cotransporter.

Losartan: Angiotensin II receptor type 1 antagonist.

Pharmacokinetics

Half-life: Furosemide — 2 hours; Losartan — 2 hours.

Chemical Properties

Molecular Formula: Furosemide — C12H11ClN2O5S; Losartan — C22H23ClN6O.

Molecular Weight: Furosemide — 330.7440 g/mol; Losartan — 422.9200 g/mol.

Type: Furosemide — Small molecule; Losartan — Small molecule.