Gabapentin vs Hydromorphone

## Gabapentin vs Hydromorphone: Overview

This comparison examines the pharmacological differences between **Gabapentin** and **Hydromorphone**.

## Mechanism of Action

**Gabapentin**: Binds alpha-2-delta subunit of voltage-gated calcium channels.

**Hydromorphone**: Semisynthetic mu-opioid receptor agonist approximately 5 times more potent than morphine.

## Pharmacokinetics

**Half-life**: Gabapentin — 5-7 hours; Hydromorphone — 2-3 hours.

## Chemical Properties

**Molecular Formula**: Gabapentin — C9H17NO2; Hydromorphone — C17H19NO3.

**Molecular Weight**: Gabapentin — 171.2370 g/mol; Hydromorphone — 285.3380 g/mol.

**Type**: Gabapentin — Small molecule; Hydromorphone — Small molecule.