Hydrochlorothiazide vs Metronidazole

## Hydrochlorothiazide vs Metronidazole: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Metronidazole**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Metronidazole**: Forms cytotoxic free radicals that damage bacterial DNA.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Metronidazole — 8 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Metronidazole — C6H9N3O3.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Metronidazole — 171.1540 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Metronidazole — Small molecule.