Hydrochlorothiazide vs Ranitidine
Hydrochlorothiazide vs Ranitidine: Overview
This comparison examines the pharmacological differences between Hydrochlorothiazide and Ranitidine.
Mechanism of Action
Hydrochlorothiazide: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.
Ranitidine: Competitive H2 receptor antagonist.
Pharmacokinetics
Half-life: Hydrochlorothiazide — 6-15 hours; Ranitidine — 2-3 hours.
Chemical Properties
Molecular Formula: Hydrochlorothiazide — C7H8ClN3O4S2; Ranitidine — C13H22N4O3S.
Molecular Weight: Hydrochlorothiazide — 297.7400 g/mol; Ranitidine — 314.4050 g/mol.
Type: Hydrochlorothiazide — Small molecule; Ranitidine — Small molecule.