Hydromorphone vs Naproxen

## Hydromorphone vs Naproxen: Overview

This comparison examines the pharmacological differences between **Hydromorphone** and **Naproxen**.

## Mechanism of Action

**Hydromorphone**: Semisynthetic mu-opioid receptor agonist approximately 5 times more potent than morphine.

**Naproxen**: Non-selective COX inhibitor.

## Pharmacokinetics

**Half-life**: Hydromorphone — 2-3 hours; Naproxen — 12-17 hours.

## Chemical Properties

**Molecular Formula**: Hydromorphone — C17H19NO3; Naproxen — C14H14O3.

**Molecular Weight**: Hydromorphone — 285.3380 g/mol; Naproxen — 230.2590 g/mol.

**Type**: Hydromorphone — Small molecule; Naproxen — Small molecule.