Ibuprofen vs Loratadine

## Ibuprofen vs Loratadine: Overview

This comparison examines the pharmacological differences between **Ibuprofen** and **Loratadine**.

## Mechanism of Action

**Ibuprofen**: Non-selective COX inhibitor reducing prostaglandin synthesis.

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

## Pharmacokinetics

**Half-life**: Ibuprofen — 2-4 hours; Loratadine — 8 hours.

## Chemical Properties

**Molecular Formula**: Ibuprofen — C13H18O2; Loratadine — C22H23ClN2O2.

**Molecular Weight**: Ibuprofen — 206.2810 g/mol; Loratadine — 382.8800 g/mol.

**Type**: Ibuprofen — Small molecule; Loratadine — Small molecule.