Ipilimumab vs Trastuzumab

## Ipilimumab vs Trastuzumab: Overview

This comparison examines the pharmacological differences between **Ipilimumab** and **Trastuzumab**.

## Mechanism of Action

**Ipilimumab**: Fully human anti-CTLA-4 IgG1 monoclonal antibody that blocks CTLA-4 inhibitory signaling.

**Trastuzumab**: Anti-HER2 monoclonal antibody inhibiting receptor signaling.

## Pharmacokinetics

**Half-life**: Ipilimumab — 14.7 days; Trastuzumab — 28 days.

## Chemical Properties

**Type**: Ipilimumab — Antibody; Trastuzumab — Antibody.