Loratadine vs Methylprednisolone

## Loratadine vs Methylprednisolone: Overview

This comparison examines the pharmacological differences between **Loratadine** and **Methylprednisolone**.

## Mechanism of Action

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

**Methylprednisolone**: Intermediate-acting synthetic glucocorticoid.

## Pharmacokinetics

**Half-life**: Loratadine — 8 hours; Methylprednisolone — 18-36 hours.

## Chemical Properties

**Molecular Formula**: Loratadine — C22H23ClN2O2; Methylprednisolone — C22H30O5.

**Molecular Weight**: Loratadine — 382.8800 g/mol; Methylprednisolone — 374.4710 g/mol.

**Type**: Loratadine — Small molecule; Methylprednisolone — Small molecule.