Loratadine vs Sertraline

## Loratadine vs Sertraline: Overview

This comparison examines the pharmacological differences between **Loratadine** and **Sertraline**.

## Mechanism of Action

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

**Sertraline**: Selective serotonin reuptake inhibitor (SSRI).

## Pharmacokinetics

**Half-life**: Loratadine — 8 hours; Sertraline — 26 hours.

## Chemical Properties

**Molecular Formula**: Loratadine — C22H23ClN2O2; Sertraline — C17H17Cl2N.

**Molecular Weight**: Loratadine — 382.8800 g/mol; Sertraline — 306.2290 g/mol.

**Type**: Loratadine — Small molecule; Sertraline — Small molecule.