Naproxen vs Tramadol

## Naproxen vs Tramadol: Overview

This comparison examines the pharmacological differences between **Naproxen** and **Tramadol**.

## Mechanism of Action

**Naproxen**: Non-selective COX inhibitor.

**Tramadol**: Mu-opioid receptor agonist and serotonin-norepinephrine reuptake inhibitor.

## Pharmacokinetics

**Half-life**: Naproxen — 12-17 hours; Tramadol — 5-7 hours.

## Chemical Properties

**Molecular Formula**: Naproxen — C14H14O3; Tramadol — C16H25NO2.

**Molecular Weight**: Naproxen — 230.2590 g/mol; Tramadol — 263.3750 g/mol.

**Type**: Naproxen — Small molecule; Tramadol — Small molecule.