Phenytoin vs Trimethoprim

## Phenytoin vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Phenytoin** and **Trimethoprim**.

## Mechanism of Action

**Phenytoin**: Sodium channel blocker stabilizing inactive state.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Phenytoin — 22 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Phenytoin — C15H12N2O2; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Phenytoin — 252.2680 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Phenytoin — Small molecule; Trimethoprim — Small molecule.