Prednisone vs Spironolactone

## Prednisone vs Spironolactone: Overview

This comparison examines the pharmacological differences between **Prednisone** and **Spironolactone**.

## Mechanism of Action

**Prednisone**: Synthetic corticosteroid; suppresses inflammation via glucocorticoid receptor.

**Spironolactone**: Mineralocorticoid receptor antagonist.

## Pharmacokinetics

**Half-life**: Prednisone — 2-3 hours; Spironolactone — 1.4 hours.

## Chemical Properties

**Molecular Formula**: Prednisone — C21H26O5; Spironolactone — C24H32O4S.

**Molecular Weight**: Prednisone — 358.4280 g/mol; Spironolactone — 416.5740 g/mol.

**Type**: Prednisone — Small molecule; Spironolactone — Small molecule.