Prednisone vs Tacrolimus

## Prednisone vs Tacrolimus: Overview

This comparison examines the pharmacological differences between **Prednisone** and **Tacrolimus**.

## Mechanism of Action

**Prednisone**: Synthetic corticosteroid; suppresses inflammation via glucocorticoid receptor.

**Tacrolimus**: Calcineurin inhibitor binding FKBP12; suppresses IL-2 transcription.

## Pharmacokinetics

**Half-life**: Prednisone — 2-3 hours; Tacrolimus — 12 hours.

## Chemical Properties

**Molecular Formula**: Prednisone — C21H26O5; Tacrolimus — C44H69NO12.

**Molecular Weight**: Prednisone — 358.4280 g/mol; Tacrolimus — 804.0180 g/mol.

**Type**: Prednisone — Small molecule; Tacrolimus — Small molecule.