Sildenafil vs Vardenafil

## Sildenafil vs Vardenafil: Overview

This comparison examines the pharmacological differences between **Sildenafil** and **Vardenafil**.

## Mechanism of Action

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Sildenafil — 4 hours; Vardenafil — N/A.

## Chemical Properties

**Molecular Formula**: Sildenafil — C22H30N6O4S; Vardenafil — N/A.

**Molecular Weight**: Sildenafil — 474.5800 g/mol; Vardenafil — N/A.

**Type**: Sildenafil — Small molecule; Vardenafil — Small molecule.