Buprenorphine vs Oxycodone

Buprenorphine vs Oxycodone: Overview

This comparison examines the pharmacological differences between Buprenorphine and Oxycodone.

Mechanism of Action

Buprenorphine: Partial mu-opioid receptor agonist and kappa antagonist with high receptor affinity.

Oxycodone: Semisynthetic mu-opioid receptor agonist.

Pharmacokinetics

Half-life: Buprenorphine — 24-42 hours; Oxycodone — 3-5 hours.

Chemical Properties

Molecular Formula: Buprenorphine — C29H41NO4; Oxycodone — C18H21NO4.

Molecular Weight: Buprenorphine — 467.6430 g/mol; Oxycodone — 315.3640 g/mol.

Type: Buprenorphine — Small molecule; Oxycodone — Small molecule.