Captopril vs Sertraline

## Captopril vs Sertraline: Overview

This comparison examines the pharmacological differences between **Captopril** and **Sertraline**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Sertraline**: Selective serotonin reuptake inhibitor (SSRI).

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Sertraline — 26 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Sertraline — C17H17Cl2N.

**Molecular Weight**: Captopril — 217.2850 g/mol; Sertraline — 306.2290 g/mol.

**Type**: Captopril — Small molecule; Sertraline — Small molecule.