Cetirizine vs Hydrochlorothiazide

Cetirizine vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between Cetirizine and Hydrochlorothiazide.

Mechanism of Action

Cetirizine: Second-generation H1 antihistamine.

Hydrochlorothiazide: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

Pharmacokinetics

Half-life: Cetirizine — 6.5-10 hours; Hydrochlorothiazide — 6-15 hours.

Chemical Properties

Molecular Formula: Cetirizine — C21H25ClN2O3; Hydrochlorothiazide — C7H8ClN3O4S2.

Molecular Weight: Cetirizine — 388.8900 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

Type: Cetirizine — Small molecule; Hydrochlorothiazide — Small molecule.