Durvalumab vs Prednisone

## Durvalumab vs Prednisone: Overview

This comparison examines the pharmacological differences between **Durvalumab** and **Prednisone**.

## Mechanism of Action

**Durvalumab**: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.

**Prednisone**: Synthetic corticosteroid; suppresses inflammation via glucocorticoid receptor.

## Pharmacokinetics

**Half-life**: Durvalumab — 17 days; Prednisone — 2-3 hours.

## Chemical Properties

**Molecular Formula**: Durvalumab — N/A; Prednisone — C21H26O5.

**Molecular Weight**: Durvalumab — N/A; Prednisone — 358.4280 g/mol.

**Type**: Durvalumab — Antibody; Prednisone — Small molecule.