Durvalumab vs Trimethoprim

## Durvalumab vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Durvalumab** and **Trimethoprim**.

## Mechanism of Action

**Durvalumab**: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Durvalumab — 17 days; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Durvalumab — N/A; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Durvalumab — N/A; Trimethoprim — 290.3180 g/mol.

**Type**: Durvalumab — Antibody; Trimethoprim — Small molecule.