Enalapril vs Lisinopril

Enalapril vs Lisinopril: Overview

This comparison examines the pharmacological differences between Enalapril and Lisinopril.

Mechanism of Action

Enalapril: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Lisinopril: ACE inhibitor preventing conversion of angiotensin I to angiotensin II.

Pharmacokinetics

Half-life: Enalapril — 11 hours; Lisinopril — 12 hours.

Chemical Properties

Molecular Formula: Enalapril — C20H28N2O5; Lisinopril — C21H31N3O5.

Molecular Weight: Enalapril — 376.4470 g/mol; Lisinopril — 405.4900 g/mol.

Type: Enalapril — Small molecule; Lisinopril — Small molecule.