Enalapril vs Losartan

## Enalapril vs Losartan: Overview

This comparison examines the pharmacological differences between **Enalapril** and **Losartan**.

## Mechanism of Action

**Enalapril**: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

**Losartan**: Angiotensin II receptor type 1 antagonist.

## Pharmacokinetics

**Half-life**: Enalapril — 11 hours; Losartan — 2 hours.

## Chemical Properties

**Molecular Formula**: Enalapril — C20H28N2O5; Losartan — C22H23ClN6O.

**Molecular Weight**: Enalapril — 376.4470 g/mol; Losartan — 422.9200 g/mol.

**Type**: Enalapril — Small molecule; Losartan — Small molecule.