Fentanyl vs Oxycodone

Fentanyl vs Oxycodone: Overview

This comparison examines the pharmacological differences between Fentanyl and Oxycodone.

Mechanism of Action

Fentanyl: Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

Oxycodone: Semisynthetic mu-opioid receptor agonist.

Pharmacokinetics

Half-life: Fentanyl — 2-4 hours; Oxycodone — 3-5 hours.

Chemical Properties

Molecular Formula: Fentanyl — C22H28N2O; Oxycodone — C18H21NO4.

Molecular Weight: Fentanyl — 336.4700 g/mol; Oxycodone — 315.3640 g/mol.

Type: Fentanyl — Small molecule; Oxycodone — Small molecule.