Fluconazole vs Vancomycin

## Fluconazole vs Vancomycin: Overview

This comparison examines the pharmacological differences between **Fluconazole** and **Vancomycin**.

## Mechanism of Action

**Fluconazole**: Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase).

**Vancomycin**: Glycopeptide antibiotic inhibiting cell wall synthesis by binding D-Ala-D-Ala terminus of peptidoglycan precursors.

## Pharmacokinetics

**Half-life**: Fluconazole — 30 hours; Vancomycin — 4-6 hours.

## Chemical Properties

**Molecular Formula**: Fluconazole — C13H12F2N6O; Vancomycin — C66H75Cl2N9O24.

**Molecular Weight**: Fluconazole — 306.2710 g/mol; Vancomycin — 1449.2500 g/mol.

**Type**: Fluconazole — Small molecule; Vancomycin — Small molecule.