Hydrochlorothiazide vs Ranitidine

Hydrochlorothiazide vs Ranitidine: Overview

This comparison examines the pharmacological differences between Hydrochlorothiazide and Ranitidine.

Mechanism of Action

Hydrochlorothiazide: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

Ranitidine: Competitive H2 receptor antagonist.

Pharmacokinetics

Half-life: Hydrochlorothiazide — 6-15 hours; Ranitidine — 2-3 hours.

Chemical Properties

Molecular Formula: Hydrochlorothiazide — C7H8ClN3O4S2; Ranitidine — C13H22N4O3S.

Molecular Weight: Hydrochlorothiazide — 297.7400 g/mol; Ranitidine — 314.4050 g/mol.

Type: Hydrochlorothiazide — Small molecule; Ranitidine — Small molecule.