Adefovir Dipivoxil

CHEMBL922 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

501.5 g/mol

LogP

1.8

Phase

4

An oral antiviral medication used to treat chronic hepatitis B infection by blocking the enzyme the hepatitis B virus uses to copy its DNA, suppressing viral replication in the liver. It is taken once daily and is particularly useful for patients whose hepatitis B has become resistant to lamivudine. Long-term use requires monitoring of kidney function, as the drug can affect the kidneys at higher doses.

Molekularmasse

501,5000 g/mol

LogP

1,80

TPSA

167,00 Å²

Lipinski-Regel der Fünf

Nicht bestanden

Therapeutische Bereiche

Hypertension Hepatitis C

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

CC(C)(C)C(=O)OCOP(=O)(COCCn1cnc2c(N)ncnc21)OCOC(=O)C(C)(C)C

InChI

InChI=1S/C20H32N5O8P/c1-19(2,3)17(26)30-11-32-34(28,33-12-31-18(27)20(4,5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H,7-8,11-13H2,1-6H3,(H2,21,22,23)

Molecular Formula

C20H32N5O8P

HBD / HBA

1 / 12

Rotierbare Bindungen

15

Schwere Atome

34

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

An oral antiviral medication used to treat chronic hepatitis B infection by blocking the enzyme the hepatitis B virus uses to copy its DNA, suppressing viral replication in the liver. It is taken once daily and is particularly useful for patients whose hepatitis B has become resistant to lamivudine. Long-term use requires monitoring of kidney function, as the drug can affect the kidneys at higher doses.

Yes, Adefovir Dipivoxil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL922. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 60871. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Schnelldaten

Formel: C20H32N5O8P
Synonyme: 1

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.