Anifrolumab

CHEMBL2364653 Phase 4 Zugelassen Antibody
Half-Life
Bioavailability
Protein Binding
Molecular Weight
g/mol
LogP
Phase
4

A monoclonal antibody that blocks the type I interferon receptor, reducing the excessive immune activation that drives tissue damage in systemic lupus erythematosus. It is given by intravenous infusion to help control lupus disease activity.

Therapeutische Bereiche

Wirkmechanismus

Binds to a specific target antigen on tumor cells or immune cells, triggering immune-mediated destruction through antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), or direct signaling inhibition.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Binds to a specific target antigen on tumor cells or immune cells, triggering immune-mediated destruction through antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), or direct signaling inhibition.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

A monoclonal antibody that blocks the type I interferon receptor, reducing the excessive immune activation that drives tissue damage in systemic lupus erythematosus. It is given by intravenous infusion to help control lupus disease activity.

Binds to a specific target antigen on tumor cells or immune cells, triggering immune-mediated destruction through antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), or direct signaling inhibition.

Yes, Anifrolumab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.

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References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2364653. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.