Benfluorex

CHEMBL400599 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
351.4 g/mol
LogP
4.6
Phase
4

A fenfluramine derivative that was used to improve glucose tolerance and lower triglycerides in type 2 diabetes, but it was withdrawn globally due to a risk of serious heart valve abnormalities.

Molekularmasse

351,4000 g/mol

LogP

4,60

TPSA

38,30 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

CC(Cc1cccc(C(F)(F)F)c1)NCCOC(=O)c1ccccc1

InChI

InChI=1S/C19H20F3NO2/c1-14(12-15-6-5-9-17(13-15)19(20,21)22)23-10-11-25-18(24)16-7-3-2-4-8-16/h2-9,13-14,23H,10-12H2,1H3

Molecular Formula

C19H20F3NO2

HBD / HBA

1 / 6

Rotierbare Bindungen

8

Schwere Atome

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

A fenfluramine derivative that was used to improve glucose tolerance and lower triglycerides in type 2 diabetes, but it was withdrawn globally due to a risk of serious heart valve abnormalities.

Yes, Benfluorex is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL400599. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 2318. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.