Calcifediol
A form of vitamin D that is the primary circulating storage form in the body, also known as 25-hydroxyvitamin D. It is used to treat secondary hyperparathyroidism and bone disease in patients with chronic kidney disease who have vitamin D deficiency. Unlike cholecalciferol, it does not require liver activation, making it useful in patients with liver disease.
Molekularmasse
400,6000 g/mol
LogP
6,20
TPSA
40,50 Ų
Lipinski-Regel der Fünf
Bestanden
Therapeutische Bereiche
Wirkmechanismus
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
2D-Struktur
Cite this structure
Embed this structure
SMILES
C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@@H]([C@H](C)CCCC(C)(C)O)CC[C@@H]12.O
InChI
InChI=1S/C27H44O2.H2O/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29;/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3;1H2/b21-11+,22-12-;/t20-,23+,24-,25+,27-;/m1./s1
Molecular Formula
C27H44O2
HBD / HBA
2 / 2
Rotierbare Bindungen
6
Schwere Atome
29
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
A form of vitamin D that is the primary circulating storage form in the body, also known as 25-hydroxyvitamin D. It is used to treat secondary hyperparathyroidism and bone disease in patients with chronic kidney disease who have vitamin D deficiency. Unlike cholecalciferol, it does not require liver activation, making it useful in patients with liver disease.
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Yes, Calcifediol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3544909. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5283731. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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