Canagliflozin Anhydrous

CHEMBL2048484 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
444.5 g/mol
LogP
3.2
Phase
4

The anhydrous form of canagliflozin, an SGLT2 inhibitor used for blood sugar management in type 2 diabetes with additional cardiovascular and renal benefits. This non-hydrated salt form is used in specific pharmaceutical formulations for stability. It shares the same mechanism and clinical profile as the standard canagliflozin formulation.

Molekularmasse

444,5000 g/mol

LogP

3,20

TPSA

118,00 Ų

Lipinski-Regel der Fünf

Bestanden

Wirkmechanismus

Selectively inhibits sodium-glucose cotransporter 2 (SGLT2) in the proximal renal tubule, reducing glucose reabsorption and promoting urinary glucose excretion. This lowers blood glucose levels independently of insulin secretion.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Selectively inhibits sodium-glucose cotransporter 2 (SGLT2) in the proximal renal tubule, reducing glucose reabsorption and promoting urinary glucose excretion. This lowers blood glucose levels independently of insulin secretion.

2D-Struktur

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SMILES

Cc1ccc([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc(-c2ccc(F)cc2)s1

InChI

InChI=1S/C24H25FO5S/c1-13-2-3-15(24-23(29)22(28)21(27)19(12-26)30-24)10-16(13)11-18-8-9-20(31-18)14-4-6-17(25)7-5-14/h2-10,19,21-24,26-29H,11-12H2,1H3/t19-,21-,22+,23-,24+/m1/s1

Molecular Formula

C24H25FO5S

HBD / HBA

4 / 7

Rotierbare Bindungen

5

Schwere Atome

31

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

The anhydrous form of canagliflozin, an SGLT2 inhibitor used for blood sugar management in type 2 diabetes with additional cardiovascular and renal benefits. This non-hydrated salt form is used in specific pharmaceutical formulations for stability. It shares the same mechanism and clinical profile as the standard canagliflozin formulation.

Selectively inhibits sodium-glucose cotransporter 2 (SGLT2) in the proximal renal tubule, reducing glucose reabsorption and promoting urinary glucose excretion. This lowers blood glucose levels independently of insulin secretion.

Yes, Canagliflozin Anhydrous is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2048484. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 24812758. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.