Carbaril

CHEMBL46917 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
201.2 g/mol
LogP
2.4
Phase
4

Also known as carbaryl, this is a carbamate insecticide occasionally used in topical formulations to treat head lice infestations that are resistant to other agents. It inhibits the enzyme acetylcholinesterase in insects, disrupting their nervous system function. Its use in humans is limited and subject to regulatory restrictions due to potential toxicity.

Molekularmasse

201,2200 g/mol

LogP

2,40

TPSA

38,30 Ų

Lipinski-Regel der Fünf

Bestanden

Wirkmechanismus

Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.

2D-Struktur

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SMILES

CNC(=O)Oc1cccc2ccccc12

InChI

InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)

Molecular Formula

C12H11NO2

HBD / HBA

1 / 2

Rotierbare Bindungen

2

Schwere Atome

15

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Also known as carbaryl, this is a carbamate insecticide occasionally used in topical formulations to treat head lice infestations that are resistant to other agents. It inhibits the enzyme acetylcholinesterase in insects, disrupting their nervous system function. Its use in humans is limited and subject to regulatory restrictions due to potential toxicity.

Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.

Yes, Carbaril is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL46917. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 6129. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.