Carbaril
Also known as carbaryl, this is a carbamate insecticide occasionally used in topical formulations to treat head lice infestations that are resistant to other agents. It inhibits the enzyme acetylcholinesterase in insects, disrupting their nervous system function. Its use in humans is limited and subject to regulatory restrictions due to potential toxicity.
分子量
201.2200 g/mol
LogP
2.40
TPSA
38.30 Ų
Lipinski 五规则
符合
作用机制
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
二维结构
Cite this structure
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SMILES
CNC(=O)Oc1cccc2ccccc12
InChI
InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)
Molecular Formula
C12H11NO2
HBD / HBA
1 / 2
可旋转键数
2
重原子数
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
Also known as carbaryl, this is a carbamate insecticide occasionally used in topical formulations to treat head lice infestations that are resistant to other agents. It inhibits the enzyme acetylcholinesterase in insects, disrupting their nervous system function. Its use in humans is limited and subject to regulatory restrictions due to potential toxicity.
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Yes, Carbaril is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL46917. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 6129. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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