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Cefotetan

CHEMBL474579 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
575.6 g/mol
LogP
0.1
Phase
4

A cephamycin antibiotic with coverage of both aerobic and anaerobic bacteria, particularly useful for intra-abdominal, pelvic, and gynecological infections. It is widely used for surgical prophylaxis in colorectal and obstetric procedures. Hypoprothrombinemia and a disulfiram-like reaction with alcohol may occur due to its N-methylthiotetrazole side chain.

Molekularmasse

575,6000 g/mol

LogP

0,10

TPSA

321,00 Ų

Lipinski-Regel der Fünf

Nicht bestanden

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CO[C@@]1(NC(=O)C2SC(=C(C(N)=O)C(=O)O)S2)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CS[C@@H]21

                

                

                
                

                    
InChI

                    
InChI=1S/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/b12-6-/t13?,15-,17+/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C17H17N7O8S4

                    

                    
                    

                        
HBD / HBA

                        
4 / 15

                    

                    
                    

                        
Rotierbare Bindungen

                        
9

                    

                    
                    
                    

                        
Schwere Atome

                        
36

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
A cephamycin antibiotic with coverage of both aerobic and anaerobic bacteria, particularly useful for intra-abdominal, pelvic, and gynecological infections. It is widely used for surgical prophylaxis in colorectal and obstetric procedures. Hypoprothrombinemia and a disulfiram-like reaction with alcohol may occur due to its N-methylthiotetrazole side chain.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Cefotetan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL474579.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 53025.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.