Cefotetan

CHEMBL474579 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

575.6 g/mol

LogP

0.1

Phase

4

A cephamycin antibiotic with coverage of both aerobic and anaerobic bacteria, particularly useful for intra-abdominal, pelvic, and gynecological infections. It is widely used for surgical prophylaxis in colorectal and obstetric procedures. Hypoprothrombinemia and a disulfiram-like reaction with alcohol may occur due to its N-methylthiotetrazole side chain.

Masse moléculaire

575,6000 g/mol

LogP

0,10

TPSA

321,00 Å²

Règle des 5 de Lipinski

Non conforme

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CO[C@@]1(NC(=O)C2SC(=C(C(N)=O)C(=O)O)S2)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CS[C@@H]21

InChI

InChI=1S/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/b12-6-/t13?,15-,17+/m1/s1

Molecular Formula

C17H17N7O8S4

HBD / HBA

4 / 15

Liaisons Rotatives

9

Atomes Lourds

36

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A cephamycin antibiotic with coverage of both aerobic and anaerobic bacteria, particularly useful for intra-abdominal, pelvic, and gynecological infections. It is widely used for surgical prophylaxis in colorectal and obstetric procedures. Hypoprothrombinemia and a disulfiram-like reaction with alcohol may occur due to its N-methylthiotetrazole side chain.

Yes, Cefotetan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL474579. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 53025. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C17H17N7O8S4
Synonymes: 1

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.