Citalopram
A selective serotonin reuptake inhibitor (SSRI) that increases serotonin availability in synapses by blocking the serotonin transporter, used to treat major depressive disorder, panic disorder, and obsessive-compulsive disorder. It has a relatively favorable side effect and drug interaction profile compared to older antidepressants. QT prolongation is a dose-dependent concern, and doses above 40 mg daily are not recommended.
Molekularmasse
324,3920 g/mol
LogP
3,20
TPSA
36,30 Ų
Lipinski-Regel der Fünf
Bestanden
Therapeutische Bereiche
Arzneimittelklassen
Wirkmechanismus
Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.
2D-Struktur
Cite this structure
Embed this structure
SMILES
CN(C)CCCC1(c2ccc(F)cc2)OCc2cc(C#N)ccc21
InChI
InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
Molecular Formula
C20H21FN2O
HBD / HBA
- / 4
Rotierbare Bindungen
5
Schwere Atome
24
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
A selective serotonin reuptake inhibitor (SSRI) that increases serotonin availability in synapses by blocking the serotonin transporter, used to treat major depressive disorder, panic disorder, and obsessive-compulsive disorder. It has a relatively favorable side effect and drug interaction profile compared to older antidepressants. QT prolongation is a dose-dependent concern, and doses above 40 mg daily are not recommended.
Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.
Key pharmacokinetic parameters for Citalopram: Half-life: 35 hours.
Yes, Citalopram is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL549. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2771. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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