Erdafitinib

CHEMBL3545376 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

446.5 g/mol

LogP

3.2

Phase

4

This oral medication blocks FGFR enzymes that are mutated or overactive in certain cancers, slowing tumor cell growth and division. It is approved for the treatment of FGFR-altered urothelial carcinoma.

Molekularmasse

446,5000 g/mol

LogP

3,20

TPSA

77,30 Å²

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Melanoma Lymphoma Breast Cancer Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

COc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1

InChI

InChI=1S/C25H30N6O2/c1-17(2)26-8-9-31(20-10-21(32-4)13-22(11-20)33-5)19-6-7-23-24(12-19)29-25(15-27-23)18-14-28-30(3)16-18/h6-7,10-17,26H,8-9H2,1-5H3

Molecular Formula

C25H30N6O2

HBD / HBA

1 / 7

Rotierbare Bindungen

9

Schwere Atome

33

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

This oral medication blocks FGFR enzymes that are mutated or overactive in certain cancers, slowing tumor cell growth and division. It is approved for the treatment of FGFR-altered urothelial carcinoma.

Yes, Erdafitinib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3545376. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 67462786. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Schnelldaten

Formel: C25H30N6O2
Synonyme: 1

Externe Links

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.