Esketamine

CHEMBL395091 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

237.7 g/mol

LogP

2.2

Phase

4

This medication works rapidly on NMDA receptors in the brain to relieve symptoms of severe or treatment-resistant depression. Unlike traditional antidepressants, it can begin to reduce depressive symptoms within hours.

Molekularmasse

237,7200 g/mol

LogP

2,20

TPSA

29,10 Å²

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Ovarian Cancer Endometriosis Pain Management Parkinson's Disease Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Infectious Disease Obesity Major Depressive Disorder Breast Cancer Chronic Pain Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure

Embed this structure

SMILES

CN[C@]1(c2ccccc2Cl)CCCCC1=O

InChI

InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3/t13-/m0/s1

Molecular Formula

C13H16ClNO

HBD / HBA

1 / 2

Rotierbare Bindungen

2

Schwere Atome

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

This medication works rapidly on NMDA receptors in the brain to relieve symptoms of severe or treatment-resistant depression. Unlike traditional antidepressants, it can begin to reduce depressive symptoms within hours.

Yes, Esketamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL395091. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 182137. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

Suchen Sie patientenfreundliche Informationen?

Esketamine auf PillFYI

Struktur

Schnelldaten

Formel: C13H16ClNO
Synonyme: 1

Externe Links

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.