Midazolam

CHEMBL655 Phase 4 Zugelassen Small molecule
Half-Life
1.5-2.5 hours
Bioavailability
Protein Binding
Molecular Weight
325.8 g/mol
LogP
2.5
Phase
4

This short-acting benzodiazepine medication produces sedation, reduces anxiety, and causes temporary memory loss, making it useful for procedural sedation and anesthesia. It acts quickly and wears off relatively fast compared to other medications in its class.

Molekularmasse

325,7670 g/mol

LogP

2,50

TPSA

30,20 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Arzneimittelklassen

Wirkmechanismus

Ultra-short-acting benzodiazepine GABA-A receptor positive allosteric modulator.

Pharmacokinetics (PK)

Half-Life 1.5-2.5 hours

Pharmacodynamics (PD)

Mechanismus

Ultra-short-acting benzodiazepine GABA-A receptor positive allosteric modulator.

2D-Struktur

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SMILES

Cc1ncc2n1-c1ccc(Cl)cc1C(c1ccccc1F)=NC2

InChI

InChI=1S/C18H13ClFN3/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13/h2-9H,10H2,1H3

Molecular Formula

C18H13ClFN3

HBD / HBA

- / 3

Rotierbare Bindungen

1

Schwere Atome

23

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

This short-acting benzodiazepine medication produces sedation, reduces anxiety, and causes temporary memory loss, making it useful for procedural sedation and anesthesia. It acts quickly and wears off relatively fast compared to other medications in its class.

Ultra-short-acting benzodiazepine GABA-A receptor positive allosteric modulator.

Key pharmacokinetic parameters for Midazolam: Half-life: 1.5-2.5 hours.

Yes, Midazolam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

Related Drugs

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References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL655. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 4192. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.